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Focus on ADFCofilin : Beyond Actin Cytoskeletal Regulation
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Actin depolymerizing factor (ADF)/cofilin, an actin-binding protein ubiquitously expressed in a variety of organisms, is required for regulation of actin dynamics.
The activity of ADF/cofilin is dependent on serine 3 phosphorylation by LIM kinase (LIMK), which is regulated by the Rho small GTPase signaling pathway.
ADF/cofilin is strongly associated with several important cell biological functions, including cell cycle, morphological maintenance, and locomotion.
These functions affect several biological events, including embryogenesis, oncology, nephropathy, and neurodegenerations.
Here, we focus on the biochemical and pathophysiological role of ADF/cofilin in mammals.
American Psychological Association (APA)
Tsai, Cheng-Han& Lee, Yi-Jang. 2012. Focus on ADFCofilin : Beyond Actin Cytoskeletal Regulation. ISRN Cell Biology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-483947
Modern Language Association (MLA)
Tsai, Cheng-Han& Lee, Yi-Jang. Focus on ADFCofilin : Beyond Actin Cytoskeletal Regulation. ISRN Cell Biology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-483947
American Medical Association (AMA)
Tsai, Cheng-Han& Lee, Yi-Jang. Focus on ADFCofilin : Beyond Actin Cytoskeletal Regulation. ISRN Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-483947
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483947