Modelling Tauopathies in Drosophila : Insights from the Fruit Fly
Joint Authors
Marcellus, Kristen
Targett, Marie-Therese
Cowan, Catherine M.
Sealey, Megan A.
Quraishe, Shmma
Allan, Douglas
Mudher, Amritpal
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-29
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Drosophila melanogaster is an experimentally tractable model organism that has been used successfully to model aspects of many human neurodegenerative diseases.
Drosophila models of tauopathy have provided valuable insights into tau-mediated mechanisms of neuronal dysfunction and death.
Here we review the findings from Drosophila models of tauopathy reported over the past ten years and discuss how they have furthered our understanding of the pathogenesis of tauopathies.
We also discuss the multitude of technical advantages that Drosophila offers, which make it highly attractive as a model for such studies.
American Psychological Association (APA)
Cowan, Catherine M.& Sealey, Megan A.& Quraishe, Shmma& Targett, Marie-Therese& Marcellus, Kristen& Allan, Douglas…[et al.]. 2011. Modelling Tauopathies in Drosophila : Insights from the Fruit Fly. International Journal of Alzheimer's Disease،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-483977
Modern Language Association (MLA)
Cowan, Catherine M.…[et al.]. Modelling Tauopathies in Drosophila : Insights from the Fruit Fly. International Journal of Alzheimer's Disease No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-483977
American Medical Association (AMA)
Cowan, Catherine M.& Sealey, Megan A.& Quraishe, Shmma& Targett, Marie-Therese& Marcellus, Kristen& Allan, Douglas…[et al.]. Modelling Tauopathies in Drosophila : Insights from the Fruit Fly. International Journal of Alzheimer's Disease. 2011. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-483977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483977