Biomarkers to Measure Treatment Effects in Alzheimer's Disease : What Should We Look for?
Author
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
It is often surprisingly difficult to tell whether a treatment for Alzheimer's disease is effective.
Biomarkers might offer the potential of a quantifiable objective measure of treatment effectiveness.
This paper suggests several criteria by which biomarkers might be evaluated as outcomes measures.
These include biological plausibility, statistical significance, dose dependence, convergence across measures, and replicability.
If biomarkers can meet these criteria, then, pending regulatory approval, they may have a role in the evaluation of treatment effectiveness in Alzheimer's disease.
If not, their usefulness may be in supplementing, but not supplanting, clinical profiles of treatment effects.
American Psychological Association (APA)
Rockwood, Kenneth. 2011. Biomarkers to Measure Treatment Effects in Alzheimer's Disease : What Should We Look for?. International Journal of Alzheimer's Disease،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-483980
Modern Language Association (MLA)
Rockwood, Kenneth. Biomarkers to Measure Treatment Effects in Alzheimer's Disease : What Should We Look for?. International Journal of Alzheimer's Disease No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-483980
American Medical Association (AMA)
Rockwood, Kenneth. Biomarkers to Measure Treatment Effects in Alzheimer's Disease : What Should We Look for?. International Journal of Alzheimer's Disease. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-483980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483980