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Low-Radiation-Dose Modified Small Bowel CT for Evaluation of Recurrent Crohn's Disease
Joint Authors
Kielar, A. Z.
McKeever, C.
Tao, H.
El-Maraghi, R. H.
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Crohn's disease affects any part of the GI tract, commonly the terminal ileum.
To decrease radiation exposure we developed a low-radiation-dose unenhanced CT (modified small Bowel CT, MBCT) to evaluate the small bowel using hyperdense oral contrast.
Technique.
MBCT was investigated in patients with pathologically proven Crohn's disease presenting with new symptoms from recurrent inflammation or stricture.
After ethics board approval, 98 consecutive patients were retrospectively evaluated.
Kappa values from two independent reviewers were calculated for presence of obstruction, active inflammation versus chronic stricture, and ancillary findings.
Forty-two patients underwent surgery or colonoscopy within 3 months.
Results.
Kappa was 0.84 for presence of abnormality versus a normal exam and 0.89 for differentiating active inflammation from chronic stricture.
Level of agreement for presence of skip areas, abscess formation, and fistula was 0.62, 0.75, and 0.78, respectively.
In the subset with “gold standard” follow-up, there was 83% agreement.
Conclusions.
MBCT is a low-radiation technique with good to very good interobserver agreement for determining presence of obstruction and degree of disease activity in patients with Crohn's disease.
Further investigation is required to refine parameters of disease activity compared to CT enterography and small bowel follow through.
American Psychological Association (APA)
Kielar, A. Z.& Tao, H.& McKeever, C.& El-Maraghi, R. H.. 2011. Low-Radiation-Dose Modified Small Bowel CT for Evaluation of Recurrent Crohn's Disease. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-484004
Modern Language Association (MLA)
Kielar, A. Z.…[et al.]. Low-Radiation-Dose Modified Small Bowel CT for Evaluation of Recurrent Crohn's Disease. Gastroenterology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-484004
American Medical Association (AMA)
Kielar, A. Z.& Tao, H.& McKeever, C.& El-Maraghi, R. H.. Low-Radiation-Dose Modified Small Bowel CT for Evaluation of Recurrent Crohn's Disease. Gastroenterology Research and Practice. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-484004
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484004