Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver
Joint Authors
Seo, Kwon Il
Ahn, Dong Uk
Nam, Ki Chang
Min, Byungrok
Du, Min
Hur, Sun Jin
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
This study was conducted to determine the effects of dietary cholesterol (CHO) and cholesterol oxidation products (COPs) on the induction of pathological lesions in rabbit liver tissues.
Liver lesions were induced only when the levels of CHO and COPs in the diet were very high.
The amount of CHO measured in the liver increased when dietary CHO was increased; by comparison, dietary COPs affected liver CHO amounts to a lesser extent.
The TBARS (thiobarbituric acid reactive substances) value measured for the liver samples also increased when dietary CHO and COP levels were elevated, and the TBARS value was more strongly affected by the amount of COPs in the diet than by the amount of CHO.
At 6 and 12 weeks, COP levels were the highest in the group that received 1.2 g CHO + 0.8 g COPs, followed by the 0.5 g CHO + 0.5 g COPs and 1.6 g CHO + 0.4 g COPs groups; the control (0 g) group showed the lowest COP levels among all groups.
In this study, we found that not only dietary CHO but also COPs were involved in hypercholesterolemia induced liver lesions when the amount of CHO and COPs was high.
American Psychological Association (APA)
Hur, Sun Jin& Nam, Ki Chang& Min, Byungrok& Du, Min& Seo, Kwon Il& Ahn, Dong Uk. 2014. Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484020
Modern Language Association (MLA)
Hur, Sun Jin…[et al.]. Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-484020
American Medical Association (AMA)
Hur, Sun Jin& Nam, Ki Chang& Min, Byungrok& Du, Min& Seo, Kwon Il& Ahn, Dong Uk. Effects of Dietary Cholesterol and Its Oxidation Products on Pathological Lesions and Cholesterol and Lipid Oxidation in the Rabbit Liver. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484020
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484020