Bone Morphogenetic Proteins in Craniofacial Surgery : Current Techniques, Clinical Experiences, and the Future of Personalized Stem Cell Therapy
Joint Authors
Chenard, Kristofer E.
Reid, Russell R.
Teven, Chad M.
He, Tong-Chuan
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-20
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Critical-size osseous defects cannot heal without surgical intervention and can pose a significant challenge to craniofacial reconstruction.
Autologous bone grafting is the gold standard for repair but is limited by a donor site morbidity and a potentially inadequate supply of autologous bone.
Alternatives to autologous bone grafting include the use of alloplastic and allogenic materials, mesenchymal stem cells, and bone morphogenetic proteins.
Bone morphogenetic proteins (BMPs) are essential mediators of bone formation involved in the regulation of differentiation of osteoprogenitor cells into osteoblasts.
Here we focus on the use of BMPs in experimental models of craniofacial surgery and clinical applications of BMPs in the reconstruction of the cranial vault, palate, and mandible and suggest a model for the use of BMPs in personalized stem cell therapies.
American Psychological Association (APA)
Chenard, Kristofer E.& Teven, Chad M.& He, Tong-Chuan& Reid, Russell R.. 2012. Bone Morphogenetic Proteins in Craniofacial Surgery : Current Techniques, Clinical Experiences, and the Future of Personalized Stem Cell Therapy. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-484107
Modern Language Association (MLA)
Chenard, Kristofer E.…[et al.]. Bone Morphogenetic Proteins in Craniofacial Surgery : Current Techniques, Clinical Experiences, and the Future of Personalized Stem Cell Therapy. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-484107
American Medical Association (AMA)
Chenard, Kristofer E.& Teven, Chad M.& He, Tong-Chuan& Reid, Russell R.. Bone Morphogenetic Proteins in Craniofacial Surgery : Current Techniques, Clinical Experiences, and the Future of Personalized Stem Cell Therapy. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-484107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484107