Different Current Intensities of Anodal Transcranial Direct Current Stimulation Do Not Differentially Modulate Motor Cortex Plasticity
Joint Authors
Young, Kayleigh
Pearce, Alan J.
Kidgell, Dawson J.
Zoghi, Maryam
Jaberzadeh, Shapour
Daly, Robin M.
Lum, Jarrod
Tooley, Gregory
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Transcranial direct current stimulation (tDCS) is a noninvasive technique that modulates the excitability of neurons within the motor cortex (M1).
Although the aftereffects of anodal tDCS on modulating cortical excitability have been described, there is limited data describing the outcomes of different tDCS intensities on intracortical circuits.
To further elucidate the mechanisms underlying the aftereffects of M1 excitability following anodal tDCS, we used transcranial magnetic stimulation (TMS) to examine the effect of different intensities on cortical excitability and short-interval intracortical inhibition (SICI).
Using a randomized, counterbalanced, crossover design, with a one-week wash-out period, 14 participants (6 females and 8 males, 22–45 years) were exposed to 10 minutes of anodal tDCS at 0.8, 1.0, and 1.2 mA.
TMS was used to measure M1 excitability and SICI of the contralateral wrist extensor muscle at baseline, immediately after and 15 and 30 minutes following cessation of anodal tDCS.
Cortical excitability increased, whilst SICI was reduced at all time points following anodal tDCS.
Interestingly, there were no differences between the three intensities of anodal tDCS on modulating cortical excitability or SICI.
These results suggest that the aftereffect of anodal tDCS on facilitating cortical excitability is due to the modulation of synaptic mechanisms associated with long-term potentiation and is not influenced by different tDCS intensities.
American Psychological Association (APA)
Kidgell, Dawson J.& Daly, Robin M.& Young, Kayleigh& Lum, Jarrod& Tooley, Gregory& Jaberzadeh, Shapour…[et al.]. 2013. Different Current Intensities of Anodal Transcranial Direct Current Stimulation Do Not Differentially Modulate Motor Cortex Plasticity. Neural Plasticity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-484297
Modern Language Association (MLA)
Kidgell, Dawson J.…[et al.]. Different Current Intensities of Anodal Transcranial Direct Current Stimulation Do Not Differentially Modulate Motor Cortex Plasticity. Neural Plasticity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-484297
American Medical Association (AMA)
Kidgell, Dawson J.& Daly, Robin M.& Young, Kayleigh& Lum, Jarrod& Tooley, Gregory& Jaberzadeh, Shapour…[et al.]. Different Current Intensities of Anodal Transcranial Direct Current Stimulation Do Not Differentially Modulate Motor Cortex Plasticity. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-484297
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484297