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Tumor Suppressors and Cell-Cycle Proteins in Lung Cancer
Joint Authors
Citro, Gennaro
De Luca, Antonio
Esposito, Vincenzo
Campioni, Mara
Spugnini, Enrico P.
Baldi, Alfonso
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-05
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The cell cycle is the cascade of events that allows a growing cell to duplicate all its components and split into two daughter cells.
Cell cycle progression is mediated by the activation of a highly conserved family of protein kinases, the cyclin-dependent kinases (CDKs).
CDKs are also regulated by related proteins called cdk inhibitors grouped into two families: the INK4 inhibitors (p16, p15, p19, and p18) and the Cip/Kip inhibitors (p21, p27, and p53).
Several studies report the importance of cell-cycle proteins in the pathogenesis and the prognosis of lung cancer.
This paper will review the most recent data from the literature about the regulation of cell cycle.
Finally, based essentially on the data generated in our laboratory, the expression, the diagnostic, and prognostic significance of cell-cycle molecules in lung cancer will be examined.
American Psychological Association (APA)
Baldi, Alfonso& De Luca, Antonio& Esposito, Vincenzo& Campioni, Mara& Spugnini, Enrico P.& Citro, Gennaro. 2011. Tumor Suppressors and Cell-Cycle Proteins in Lung Cancer. Pathology Research International،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-484444
Modern Language Association (MLA)
Baldi, Alfonso…[et al.]. Tumor Suppressors and Cell-Cycle Proteins in Lung Cancer. Pathology Research International No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-484444
American Medical Association (AMA)
Baldi, Alfonso& De Luca, Antonio& Esposito, Vincenzo& Campioni, Mara& Spugnini, Enrico P.& Citro, Gennaro. Tumor Suppressors and Cell-Cycle Proteins in Lung Cancer. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-484444
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484444