Hearing and Neurological Impairment in Children with History of Exchange Transfusion for Neonatal Hyperbilirubinemia
Joint Authors
Poblano, Adrián
Martínez-Cruz, Carlos F.
García Alonso-Themann, Patricia
Cedillo-Rodríguez, Ileana A.
Source
International Journal of Pediatrics
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The objective was to determine frequency of sensorineural hearing loss (SNHL), identified by abnormal threshold in evoked potentials, absence of otoacoustic emissions and behavioral responses, auditory neuropathy (AN) (absence of evoked potentials, with preservation of otoacoustic emissions), and neurological comorbidity in infants with hyperbilirubinemia (HB) treated with exchange-transfusion (ET).
From a total of 7,219 infants, ET was performed on 336 (4.6%).
Inclusion criteria were fulfilled in 102; 234 children did not meet criteria (182 outside of the study period, 34 did not have complete audiological evaluation, and 18 rejected the followup).
Thirty-five children (34%) were born at-term and 67 (66%) were preterm.
Children had a mean age of 5.5±3.9 years.
Main causes of ET were Rh isoimmunization in 48 (47%), ABO incompatibility in 28 (27.5%), and multifactorial causes in 26 (25.5%).
Fifteen (15%) children presented with SNHL.
Preterm newborns presented more often with SNHL.
Indirect bilirubin level was higher in children with SNHL (22.2 versus 18.7 mg/dL, P=0.02).
No cases of AN were documented.
An increased risk of neurologic sequelae was observed in children with SNHL.
In conclusion, we disclosed a high frequency of SNHL in children with neonatal HB and ET and neurological alterations.
No cases of AN were observed.
American Psychological Association (APA)
Martínez-Cruz, Carlos F.& García Alonso-Themann, Patricia& Poblano, Adrián& Cedillo-Rodríguez, Ileana A.. 2014. Hearing and Neurological Impairment in Children with History of Exchange Transfusion for Neonatal Hyperbilirubinemia. International Journal of Pediatrics،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484516
Modern Language Association (MLA)
Martínez-Cruz, Carlos F.…[et al.]. Hearing and Neurological Impairment in Children with History of Exchange Transfusion for Neonatal Hyperbilirubinemia. International Journal of Pediatrics No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-484516
American Medical Association (AMA)
Martínez-Cruz, Carlos F.& García Alonso-Themann, Patricia& Poblano, Adrián& Cedillo-Rodríguez, Ileana A.. Hearing and Neurological Impairment in Children with History of Exchange Transfusion for Neonatal Hyperbilirubinemia. International Journal of Pediatrics. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484516
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484516