Effect of Delay on Selection Dynamics in Long-Term Sphere Culture of Cancer Stem Cells

Joint Authors

Li, Jianquan
Fan, Aijun
Jiang, Jun
Tang, Peng
Wang, Kaifa

Source

Discrete Dynamics in Nature and Society

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-03-20

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Mathematics

Abstract EN

To quantitatively study the effect of delay on selection dynamics in long-term sphere culture of cancer stem cells (CSCs), a selection dynamic model with time delay is proposed.

Theoretical results show that the ubiquitous time delay in cell proliferation may be one of the important factors to induce fluctuation, and numerical simulations indicate that the proposed selection dynamical model with time delay can provide a better fitting effect for the experiment of a long-term sphere culture of CSCs.

Thus, it is valuable to consider the delay effect in the future study on the dynamics of nongenetic heterogeneity of clonal cell populations.

American Psychological Association (APA)

Tang, Peng& Fan, Aijun& Li, Jianquan& Jiang, Jun& Wang, Kaifa. 2013. Effect of Delay on Selection Dynamics in Long-Term Sphere Culture of Cancer Stem Cells. Discrete Dynamics in Nature and Society،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-484550

Modern Language Association (MLA)

Tang, Peng…[et al.]. Effect of Delay on Selection Dynamics in Long-Term Sphere Culture of Cancer Stem Cells. Discrete Dynamics in Nature and Society No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-484550

American Medical Association (AMA)

Tang, Peng& Fan, Aijun& Li, Jianquan& Jiang, Jun& Wang, Kaifa. Effect of Delay on Selection Dynamics in Long-Term Sphere Culture of Cancer Stem Cells. Discrete Dynamics in Nature and Society. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-484550

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-484550