Inflammation and Oxidative Stress in Obesity-Related Glomerulopathy
Joint Authors
Zhuang, Shougang
Yan, Haidong
Tang, Jinhua
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Obesity-related glomerulopathy is an increasing cause of end-stage renal disease.
Obesity has been considered a state of chronic low-grade systemic inflammation and chronic oxidative stress.
Augmented inflammation in adipose and kidney tissues promotes the progression of kidney damage in obesity.
Adipose tissue, which is accumulated in obesity, is a key endocrine organ that produces multiple biologically active molecules, including leptin, adiponectin, resistin, that affect inflammation, and subsequent deregulation of cell function in renal glomeruli that leads to pathological changes.
Oxidative stress is also associated with obesity-related renal diseases and may trigger the initiation or progression of renal damage in obesity.
In this paper, we focus on inflammation and oxidative stress in the progression of obesity-related glomerulopathy and possible interventions to prevent kidney injury in obesity.
American Psychological Association (APA)
Tang, Jinhua& Yan, Haidong& Zhuang, Shougang. 2012. Inflammation and Oxidative Stress in Obesity-Related Glomerulopathy. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-484746
Modern Language Association (MLA)
Tang, Jinhua…[et al.]. Inflammation and Oxidative Stress in Obesity-Related Glomerulopathy. International Journal of Nephrology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-484746
American Medical Association (AMA)
Tang, Jinhua& Yan, Haidong& Zhuang, Shougang. Inflammation and Oxidative Stress in Obesity-Related Glomerulopathy. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-484746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484746