Undifferentiated Endometrial Sarcoma of the Ovary : A Case Report with Review of Recent Literature and Discussion of Lacking Specificity of CD10 Immunoreactivity
Joint Authors
Geiss, Ingrid M.
Brustmann, Hermann
Hinterholzer, Susanne
Source
Pathology Research International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-10-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Undifferentiated endometrial sarcomas (UESs) of the ovary are very rare tumors.
This paper presents a case of a 56-year-old patient with a history of hysterectomy and bilateral salpingectomy seven years ago for uterine leiomyomata.
Intraoperatively, a tumor originating from the left ovary, adherent to the sigmoid colon, with infiltration of the small intestine and the vaginal apex was found.
Histologically, the tumor was composed of pleomorphic round and oval to spindled cells with polymorphous vesicular nuclei with coarse chromatin and large nucleoli.
Mitotic activity was brisk.
There were large necrotic areas.
Adjacent to the tumor tissue endometrium-like glands surrounded by fibrous stroma with macrophages corresponding to ovarian endometriosis were noted.
Tumor cells showed diffuse strong immunoreactivity for vimentin and patchy strong staining for CD10; no reactivities were found for AE1/AE3, desmin, S-100, LCA, CD20, c-kit, and CD31.
The patient died of her neoplastic disease four months postoperatively.
CD10 is frequently expressed in different gynecopathological as well as other lesions, and, thus, nonspecific without relevance to the classification of this case.
Morphological features, extensive sampling, and appropriate immunohistochemistry including markers for cytokeratins and myogenic differentiation are mandatory to arrive at the correct diagnosis.
American Psychological Association (APA)
Brustmann, Hermann& Geiss, Ingrid M.& Hinterholzer, Susanne. 2009. Undifferentiated Endometrial Sarcoma of the Ovary : A Case Report with Review of Recent Literature and Discussion of Lacking Specificity of CD10 Immunoreactivity. Pathology Research International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-484756
Modern Language Association (MLA)
Brustmann, Hermann…[et al.]. Undifferentiated Endometrial Sarcoma of the Ovary : A Case Report with Review of Recent Literature and Discussion of Lacking Specificity of CD10 Immunoreactivity. Pathology Research International No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-484756
American Medical Association (AMA)
Brustmann, Hermann& Geiss, Ingrid M.& Hinterholzer, Susanne. Undifferentiated Endometrial Sarcoma of the Ovary : A Case Report with Review of Recent Literature and Discussion of Lacking Specificity of CD10 Immunoreactivity. Pathology Research International. 2009. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-484756
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484756