The Role of Klebsiella in Crohn’s Disease with a Potential for the Use of Antimicrobial Measures
Joint Authors
Rashid, Taha
Ebringer, Alan
Wilson, Clyde
Source
International Journal of Rheumatology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
There is a general consensus that Crohn’s disease (CD) develops as the result of immune-mediated tissue damage triggered by infections with intestinal microbial agents.
Based on the results of existing microbiological, molecular, and immunological studies, Klebsiella microbe seems to have a key role in the initiation and perpetuation of the pathological damage involving the gut and joint tissues in patients with CD.
Six different gastroenterology centres in the UK have reported elevated levels of antibodies to Klebsiella in CD patients.
There is a relationship between high intake of starch-containing diet, enhanced growth of gut microbes, and the production of pullulanases by Klebsiella.
It is proposed that eradication of these microbes by the use of antibiotics and low starch diet, in addition to the currently used treatment, could help in alleviating or halting the disease process in CD.
American Psychological Association (APA)
Rashid, Taha& Ebringer, Alan& Wilson, Clyde. 2013. The Role of Klebsiella in Crohn’s Disease with a Potential for the Use of Antimicrobial Measures. International Journal of Rheumatology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-484938
Modern Language Association (MLA)
Rashid, Taha…[et al.]. The Role of Klebsiella in Crohn’s Disease with a Potential for the Use of Antimicrobial Measures. International Journal of Rheumatology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-484938
American Medical Association (AMA)
Rashid, Taha& Ebringer, Alan& Wilson, Clyde. The Role of Klebsiella in Crohn’s Disease with a Potential for the Use of Antimicrobial Measures. International Journal of Rheumatology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-484938
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484938