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Macrophage Migration Inhibitory Factor : Critical Role in Obesity, Insulin Resistance, and Associated Comorbidities
Joint Authors
Bucala, Richard
Kleemann, Robert
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Obesity is associated with insulin resistance, disturbed glucose homeostasis, low grade inflammation, and comorbidities such as type 2 diabetes and cardiovascular disease.
The cytokine macrophage migration inhibitory factor (MIF) is an ubiquitously expressed protein that plays a crucial role in many inflammatory and autoimmune disorders.
Increasing evidence suggests that MIF also controls metabolic and inflammatory processes underlying the development of metabolic pathologies associated with obesity.
This is a comprehensive summary of our current knowledge on the role of MIF in obesity and obesity-associated comorbidities, based on human clinical data as well as animal models of disease.
American Psychological Association (APA)
Kleemann, Robert& Bucala, Richard. 2010. Macrophage Migration Inhibitory Factor : Critical Role in Obesity, Insulin Resistance, and Associated Comorbidities. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-484951
Modern Language Association (MLA)
Kleemann, Robert& Bucala, Richard. Macrophage Migration Inhibitory Factor : Critical Role in Obesity, Insulin Resistance, and Associated Comorbidities. Mediators of Inflammation No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-484951
American Medical Association (AMA)
Kleemann, Robert& Bucala, Richard. Macrophage Migration Inhibitory Factor : Critical Role in Obesity, Insulin Resistance, and Associated Comorbidities. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-484951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484951