Left Atrial Appendage Exclusion for Stroke Prevention in Atrial Fibrillation
Joint Authors
Patel, Taral K.
Knight, Bradley P.
Yancy, Clyde W.
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The public health burden of atrial fibrillation (AF) and associated thromboembolic stroke continues to grow at alarming rates.
AF leads to a fivefold increase in the risk of stroke.
Therefore, stroke prevention remains the most critical aspect of AF management.
Current standard of care focuses on oral systemic anticoagulation, most commonly with warfarin and now with newer agents such as dabigatran, rivaroxaban, and apixaban.
However, the challenges and limitations of oral anticoagulation have been well documented.
Given the critical role of the left atrial appendage (LAA) in the genesis of AF-related thromboembolism, recent efforts have targeted removal or occlusion of the LAA as an alternative strategy for stroke prevention, particularly in patients deemed unsuitable for oral anticoagulation.
This paper highlights recent advances in mechanical exclusion of the LAA.
The problem of AF and stroke is briefly summarized, followed by an explanation for the rationale behind LAA exclusion for stroke prevention.
After briefly reviewing the history of LAA exclusion, we highlight the most promising LAA exclusion devices currently available.
Finally, we discuss future challenges and opportunities in this growing field.
American Psychological Association (APA)
Patel, Taral K.& Yancy, Clyde W.& Knight, Bradley P.. 2012. Left Atrial Appendage Exclusion for Stroke Prevention in Atrial Fibrillation. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-484995
Modern Language Association (MLA)
Patel, Taral K.…[et al.]. Left Atrial Appendage Exclusion for Stroke Prevention in Atrial Fibrillation. Cardiology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-484995
American Medical Association (AMA)
Patel, Taral K.& Yancy, Clyde W.& Knight, Bradley P.. Left Atrial Appendage Exclusion for Stroke Prevention in Atrial Fibrillation. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-484995
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-484995