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Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia
Joint Authors
Lin, Xiaoming
Yan, Xiaohe
Ding, Kun
Liu, Yong
Jiang, Tianzi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Amblyopia, which usually occurs during early childhood and results in poor or blurred vision, is a disorder of the visual system that is characterized by a deficiency in an otherwise physically normal eye or by a deficiency that is out of proportion with the structural or functional abnormalities of the eye.
Our previous study demonstrated alterations in the spontaneous activity patterns of some brain regions in individuals with anisometropic amblyopia compared to subjects with normal vision.
To date, it remains unknown whether patients with amblyopia show characteristic alterations in the functional connectivity patterns in the visual areas of the brain, particularly the primary visual area.
In the present study, we investigated the differences in the functional connectivity of the primary visual area between individuals with amblyopia and normal-sighted subjects using resting functional magnetic resonance imaging.
Our findings demonstrated that the cerebellum and the inferior parietal lobule showed altered functional connectivity with the primary visual area in individuals with amblyopia, and this finding provides further evidence for the disruption of the dorsal visual pathway in amblyopic subjects.
American Psychological Association (APA)
Ding, Kun& Liu, Yong& Yan, Xiaohe& Lin, Xiaoming& Jiang, Tianzi. 2013. Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia. Neural Plasticity،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-485024
Modern Language Association (MLA)
Ding, Kun…[et al.]. Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia. Neural Plasticity No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-485024
American Medical Association (AMA)
Ding, Kun& Liu, Yong& Yan, Xiaohe& Lin, Xiaoming& Jiang, Tianzi. Altered Functional Connectivity of the Primary Visual Cortex in Subjects with Amblyopia. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-485024
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485024