The Basis of Muscle Regeneration
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-09
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Muscle regeneration recapitulates many aspects of embryonic myogenesis and is an important homeostatic process of the adult skeletal muscle, which, after development, retains the capacity to regenerate in response to appropriate stimuli, activating the muscle compartment of stem cells, namely, satellite cells, as well as other precursor cells.
Moreover, significant evidence suggests that while stem cells represent an important determinant for tissue regeneration, a “qualified” environment is necessary to guarantee and achieve functional results.
It is therefore plausible that the loss of control over these cell fate decisions could lead to a pathological transdifferentiation, leading to pathologic defects in the regenerative process.
This review provides an overview about the general aspects of muscle development and discusses the cellular and molecular aspects that characterize the five interrelated and time-dependent phases of muscle regeneration, namely, degeneration, inflammation, regeneration, remodeling, and maturation/functional repair.
American Psychological Association (APA)
Musarò, Antonio. 2014. The Basis of Muscle Regeneration. Advances in Biology،Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-485054
Modern Language Association (MLA)
Musarò, Antonio. The Basis of Muscle Regeneration. Advances in Biology No. 2014 (2014), pp.1-16.
https://search.emarefa.net/detail/BIM-485054
American Medical Association (AMA)
Musarò, Antonio. The Basis of Muscle Regeneration. Advances in Biology. 2014. Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-485054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485054