Comparison of a Multiple Daily Insulin Injection Regimen (Glargine or Detemir Once Daily Plus Prandial Insulin Aspart) and Continuous Subcutaneous Insulin Infusion (Aspart) in Short-Term Intensive Insulin Therapy for Poorly Controlled Type 2 Diabetes Patients
Joint Authors
Sun, Rui-xia
Lv, Wen-shan
Li, Li
Gao, Yan-yan
Wang, Jing
Pan, Rong-fang
Cao, Cai-xia
Xian, Yu-xin
Wen, Jun-ping
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aims.
To examine the potential differences between multiple daily injection (MDI) regimens based on new long-acting insulin analogues (glargine or detemir) plus prandial insulin aspart and continuous subcutaneous insulin aspart infusion (CSII) in patients with poorly controlled type 2 diabetes.
Methods.
Patients (n=119) with poorly controlled type 2 diabetes of a duration exceeding five years were randomly assigned into three groups: Group A treated with CSII using insulin aspart; Group B treated with glargine-based MDI and Group C treated with detemir-based MDI.
Results.
Good glycemic control was achieved by patients in Group A in a significantly shorter duration than patients in Groups B and C.
Total daily insulin, basal insulin dose and dose per kg body weight in Group A were significantly less than those in Groups B and C.
Daily blood glucose fluctuation in Group A was significantly less than that in Groups B and C.
There were no differences between Groups B and C.
Conclusions.
Aspart-based CSII may achieve good blood glucose control with less insulin doses over a shorter period compared with glargine or detemir-based MDI.
No differences between glargine- and detemir-based MDI were detected in poorly controlled subjects with type 2 diabetes.
American Psychological Association (APA)
Lv, Wen-shan& Li, Li& Wen, Jun-ping& Pan, Rong-fang& Sun, Rui-xia& Wang, Jing…[et al.]. 2013. Comparison of a Multiple Daily Insulin Injection Regimen (Glargine or Detemir Once Daily Plus Prandial Insulin Aspart) and Continuous Subcutaneous Insulin Infusion (Aspart) in Short-Term Intensive Insulin Therapy for Poorly Controlled Type 2 Diabetes Patients. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-485214
Modern Language Association (MLA)
Lv, Wen-shan…[et al.]. Comparison of a Multiple Daily Insulin Injection Regimen (Glargine or Detemir Once Daily Plus Prandial Insulin Aspart) and Continuous Subcutaneous Insulin Infusion (Aspart) in Short-Term Intensive Insulin Therapy for Poorly Controlled Type 2 Diabetes Patients. International Journal of Endocrinology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-485214
American Medical Association (AMA)
Lv, Wen-shan& Li, Li& Wen, Jun-ping& Pan, Rong-fang& Sun, Rui-xia& Wang, Jing…[et al.]. Comparison of a Multiple Daily Insulin Injection Regimen (Glargine or Detemir Once Daily Plus Prandial Insulin Aspart) and Continuous Subcutaneous Insulin Infusion (Aspart) in Short-Term Intensive Insulin Therapy for Poorly Controlled Type 2 Diabetes Patients. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-485214
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485214