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Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma
Joint Authors
Leon, Marino E.
Zarineh, Alireza
Saad, Reda S.
Silverman, Jan F.
Source
Pathology Research International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-09-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Primary or idiopathic hypertrophy of the pyloric muscle (IHPM) is a rare entity with uncertain pathogenesis which both clinically and pathologically mimics gastric cancer.
We present a rare late-occurring case of IHPM in a 71-year-old Caucasian man with no apparent predisposing factor.
Imaging studies demonstrated gastric distension with air fluid levels and no evidence of extrinsic compression.
At upper endoscopy, massive gastric distension and no evidence of any ulcer or other mucosal defects were observed.
Microscopically, marked hypertrophy of muscularis mucosa with smooth muscle cells arranged in whorls and fascicles was present which gradually transitioned to normal areas.
The muscle fibers stained with smooth muscle actin and trichrome stain highlighted fibrosis between the muscle fibers.
Although uncommon, IHPM can clinically and histologically mimic other proliferations in the gastric wall, such as gastrointestinal stromal tumor or a spindle cell neoplasm.
The recent advances in understanding the pathogenesis of IHPM are discussed.
American Psychological Association (APA)
Zarineh, Alireza& Leon, Marino E.& Saad, Reda S.& Silverman, Jan F.. 2009. Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma. Pathology Research International،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-485221
Modern Language Association (MLA)
Zarineh, Alireza…[et al.]. Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma. Pathology Research International No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-485221
American Medical Association (AMA)
Zarineh, Alireza& Leon, Marino E.& Saad, Reda S.& Silverman, Jan F.. Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma. Pathology Research International. 2009. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-485221
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485221