Pretransplant Fasting Glucose Predicts New-Onset Diabetes after Liver Transplantation
Joint Authors
Chakkera, Harini A.
Carey, Elizabeth J.
Reddy, K. Sudhakar
Rakela, Jorge
Douglas, David D.
Mulligan, David C.
Moss, Adyr A.
Aqel, Bashar A.
Vargas, Hugo E.
Byrne, Thomas J.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
New-onset diabetes after transplantation (NODAT) is common after liver transplant and associated with poorer outcomes.
The aim of this study was to identify risk factors for NODAT in liver transplant recipients off corticosteroids.
In 225 adult nondiabetic liver transplant recipients, the mean age was 51.7 years, the majority were men (71%), and half had HCV (49%).
The mean calculated MELD score at transplantation was 18.7, and 19% underwent living-donor transplant (LDLT).
One year after transplantation, 17% developed NODAT, and an additional 16% had impaired fasting glucose.
The incidence of NODAT in patients with HCV was 26%.
In multivariate analysis, HCV, pretransplant FPG, and LDLT were significant.
Each 10 mg/dL increase in pretransplant FPG was associated with a twofold increase in future development of NODAT.
The incidence of NODAT after liver transplant in patients off corticosteroids is 17%.
Risk factors for developing NODAT include HCV and pretransplant FPG; LDLT is protective.
American Psychological Association (APA)
Carey, Elizabeth J.& Aqel, Bashar A.& Byrne, Thomas J.& Douglas, David D.& Rakela, Jorge& Vargas, Hugo E.…[et al.]. 2012. Pretransplant Fasting Glucose Predicts New-Onset Diabetes after Liver Transplantation. Journal of Transplantation،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-485268
Modern Language Association (MLA)
Carey, Elizabeth J.…[et al.]. Pretransplant Fasting Glucose Predicts New-Onset Diabetes after Liver Transplantation. Journal of Transplantation No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-485268
American Medical Association (AMA)
Carey, Elizabeth J.& Aqel, Bashar A.& Byrne, Thomas J.& Douglas, David D.& Rakela, Jorge& Vargas, Hugo E.…[et al.]. Pretransplant Fasting Glucose Predicts New-Onset Diabetes after Liver Transplantation. Journal of Transplantation. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-485268
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485268