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Mechanism of Trypanosoma cruzi Placenta Invasion and Infection : The Use of Human Chorionic Villi Explants
Joint Authors
Fretes, Ricardo E.
Kemmerling, Ulrike
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Congenital Chagas disease, a neglected tropical disease, endemic in Latin America, is associated with premature labor and miscarriage.
During vertical transmission the parasite Trypanosoma cruzi (T.
cruzi) crosses the placental barrier.
However, the exact mechanism of the placental infection remains unclear.
We review the congenital transmission of T.
cruzi, particularly the role of possible local placental factors that contribute to the vertical transmission of the parasite.
Additionally, we analyze the different methods available for studying the congenital transmission of the parasite.
In that context, the ex vivo infection with T.
cruzi trypomastigotes of human placental chorionic villi constitutes an excellent tool for studying parasite infection strategies as well as possible local antiparasitic mechanisms.
American Psychological Association (APA)
Fretes, Ricardo E.& Kemmerling, Ulrike. 2012. Mechanism of Trypanosoma cruzi Placenta Invasion and Infection : The Use of Human Chorionic Villi Explants. Journal of Tropical Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-485273
Modern Language Association (MLA)
Fretes, Ricardo E.& Kemmerling, Ulrike. Mechanism of Trypanosoma cruzi Placenta Invasion and Infection : The Use of Human Chorionic Villi Explants. Journal of Tropical Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-485273
American Medical Association (AMA)
Fretes, Ricardo E.& Kemmerling, Ulrike. Mechanism of Trypanosoma cruzi Placenta Invasion and Infection : The Use of Human Chorionic Villi Explants. Journal of Tropical Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-485273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485273