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Ultrasonographic Prevalence and Factors Predicting Left Ventricular Diastolic Dysfunction in Patients with Liver Cirrhosis : Is There a Correlation between the Grade of Diastolic Dysfunction and the Grade of Liver Disease?
Joint Authors
Giakoumakis, Tsampikos
Papastergiou, Vasilios
Ntousikos, Konstantinos
Karatapanis, Stylianos
Lisgos, Phillipos
Papakonstantinou, Nikolaos
Skorda, Lamprini
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Presence of cardiac dysfunction has been associated with an unfavorable prognosis in patients with liver cirrhosis.
In the present study, 92 consecutive, newly-diagnosed patients with liver cirrhosis were prospectively evaluated.
Liver disease was graded according to the modified Child-Turcotte-Pugh (CTP) score whereas left ventricular diastolic function was assessed by Doppler-echocardiography and graded (Stage 0 to 4) according to current guidelines.
Overall, DD was diagnosed in 55/92 (59.8%) patients [DD-stage-1: 36/92 (39.1%), DD-stage-2: 19/92 (20.6%)].
Prevalence of DD-stage-1 among the different stages of liver cirrhosis was: CTP-class A: 11/29 (37.9%), B: 15/39 (38.5%), C: 10/24 (41.6%), (P>0.05 in all comparisons), whereas for DD-stage-2 the corresponding proportions were CTP-class A: 3/29 (10.3%), B: 5/39 (12.8%), C: 11/24 (45.8%), (P=0.0009 between CTP-class C versus A and B).
Age > 53 years (Odd’s Ratio [OR]: 4.2; 95% confidence interval [CI]: 1.5–12.1) and CTP-class C (OR: 4.6; 95% CI: 1.1–20) could independently predict DD.
No relation between presence of DD and the etiology of the liver disease was found.
We conclude that DD is a common feature in liver cirrhosis.
DD-stage-1 is fairly prevalent among all CTP-classes whereas DD-stage-2 seems to be characteristic of the advanced liver disease (CTP-class C).
A high level of awareness for the presence of the syndrome is required, especially if cirrhotic patients are CTP-class C and/or of older age.
American Psychological Association (APA)
Papastergiou, Vasilios& Skorda, Lamprini& Lisgos, Phillipos& Papakonstantinou, Nikolaos& Giakoumakis, Tsampikos& Ntousikos, Konstantinos…[et al.]. 2012. Ultrasonographic Prevalence and Factors Predicting Left Ventricular Diastolic Dysfunction in Patients with Liver Cirrhosis : Is There a Correlation between the Grade of Diastolic Dysfunction and the Grade of Liver Disease?. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-485294
Modern Language Association (MLA)
Papastergiou, Vasilios…[et al.]. Ultrasonographic Prevalence and Factors Predicting Left Ventricular Diastolic Dysfunction in Patients with Liver Cirrhosis : Is There a Correlation between the Grade of Diastolic Dysfunction and the Grade of Liver Disease?. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-485294
American Medical Association (AMA)
Papastergiou, Vasilios& Skorda, Lamprini& Lisgos, Phillipos& Papakonstantinou, Nikolaos& Giakoumakis, Tsampikos& Ntousikos, Konstantinos…[et al.]. Ultrasonographic Prevalence and Factors Predicting Left Ventricular Diastolic Dysfunction in Patients with Liver Cirrhosis : Is There a Correlation between the Grade of Diastolic Dysfunction and the Grade of Liver Disease?. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-485294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485294