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Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer
Joint Authors
Terstappen, Leon W. M. M.
Miller, M. Craig
Doyle, Gerald V.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The increasing number of treatment options for patients with metastatic carcinomas has created a concomitant need for new methods to monitor their use.
Ideally, these modalities would be noninvasive, be independent of treatment, and provide quantitative real-time analysis of tumor activity in a variety of carcinomas.
Assessment of circulating tumor cells (CTCs) shed into the blood during metastasis may satisfy this need.
We developed the CellSearch System to enumerate CTC from 7.5 mL of venous blood.
In this review we compare the outcomes from three prospective multicenter studies investigating the use of CTC to monitor patients undergoing treatment for metastatic breast (MBC), colorectal (MCRC), or prostate cancer (MPC) and review the CTC definition used in these studies.
Evaluation of CTC at anytime during the course of disease allows assessment of patient prognosis and is predictive of overall survival.
American Psychological Association (APA)
Miller, M. Craig& Doyle, Gerald V.& Terstappen, Leon W. M. M.. 2009. Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer. Journal of Oncology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-485491
Modern Language Association (MLA)
Miller, M. Craig…[et al.]. Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer. Journal of Oncology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-485491
American Medical Association (AMA)
Miller, M. Craig& Doyle, Gerald V.& Terstappen, Leon W. M. M.. Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer. Journal of Oncology. 2009. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-485491
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485491