Age-Related White Matter Changes

Joint Authors

Mok, V. C. T.
Xiong, Yun Yun

Source

Journal of Aging Research

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-08-23

Country of Publication

Egypt

No. of Pages

13

Main Subjects

Pharmacy, Health & Medical Sciences

Abstract EN

Age-related white matter changes (WMC) are considered manifestation of arteriolosclerotic small vessel disease and are related to age and vascular risk factors.

Most recent studies have shown that WMC are associated with a host of poor outcomes, including cognitive impairment, dementia, urinary incontinence, gait disturbances, depression, and increased risk of stroke and death.

Although the clinical relevance of WMC has been extensively studied, to date, only very few clinical trials have evaluated potential symptomatic or preventive treatments for WMC.

In this paper, we reviewed the current understanding in the pathophysiology, epidemiology, clinical importance, chemical biomarkers, and treatments of age-related WMC.

American Psychological Association (APA)

Xiong, Yun Yun& Mok, V. C. T.. 2011. Age-Related White Matter Changes. Journal of Aging Research،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-485537

Modern Language Association (MLA)

Xiong, Yun Yun& Mok, V. C. T.. Age-Related White Matter Changes. Journal of Aging Research No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-485537

American Medical Association (AMA)

Xiong, Yun Yun& Mok, V. C. T.. Age-Related White Matter Changes. Journal of Aging Research. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-485537

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-485537