Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase)‎ in Acute Ischemic Stroke

Joint Authors

Arunachalam, Sumathy
Thomas, Binny
Sivanandy, Palanisamy
Krishnan, Vijayan

Source

ISRN Neurology

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-11-29

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

The aim of this study was to evaluate the efficacy and safety of thrombolytic therapy.

Our study enrolled 23 patients out of which 2 patients died due to ICH; we also found that only 39% of patients reached hospital within stroke window, and for those treated, mean NIHSS during admission was 14.0, but drastic improvement was shown after 24 hours of treatment, that is, 9.89 (P<0.0001), and at discharge, it was 5.1 (P<0.0001) which showed a clear impact of the treatment, and around 60% of patients were discharged within an mRS score of 1 and 2.

Hence, it was found that thrombolytic therapy was beneficial, efficacious, and safe if used within 3 to 4.5 hours.

American Psychological Association (APA)

Sivanandy, Palanisamy& Thomas, Binny& Krishnan, Vijayan& Arunachalam, Sumathy. 2011. Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase) in Acute Ischemic Stroke. ISRN Neurology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-485601

Modern Language Association (MLA)

Sivanandy, Palanisamy…[et al.]. Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase) in Acute Ischemic Stroke. ISRN Neurology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-485601

American Medical Association (AMA)

Sivanandy, Palanisamy& Thomas, Binny& Krishnan, Vijayan& Arunachalam, Sumathy. Safety and Efficacy of Thrombolytic Therapy Using rt-PA (Alteplase) in Acute Ischemic Stroke. ISRN Neurology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-485601

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-485601