Takayasu Arteritis : Criteria for Surgical Intervention Should Not Be Ignored
Joint Authors
Mason, J. C.
Wolfe, J. H.
Perera, A. H.
Source
International Journal of Vascular Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Takayasu aortoarteritis is a rare, chronic granulomatous panarteritis with significant morbidity amongst young patients.
Current challenges include a lack of awareness about the condition, delays in diagnosis due to its varied presentation, and suboptimal methods for assessing disease activity.
The development of noninvasive imaging including magnetic resonance angiography and positron emission tomography is aiding earlier diagnosis.
Early initiation of immunosuppressive treatment is crucial to control active inflammation and minimize arterial injury.
Recent studies investigating biological agents such as tumour necrosis factor-α antagonists are encouraging.
Surgical revascularization should only be undertaken following careful consideration, as restenosis is common.
The indications for considering intervention include uncontrolled hypertension due to renal artery stenosis, severe symptomatic coronary artery or cerebrovascular disease, severe aortic regurgitation, stenotic or occlusive lesions resulting in critical limb ischemia, and aneurysms at risk of rupture.
In these cases, the risk benefit ratio for intervention is good.
Open surgery, at present, has better outcomes compared to endovascular techniques.
However, technological advances in endovascular treatment are continually improving.
Controlling disease activity prior to and following revascularization is key to preventing complications.
A multidisciplinary approach to the diagnosis and management of Takayasu arteritis is essential to achieve satisfactory patient outcomes.
American Psychological Association (APA)
Perera, A. H.& Mason, J. C.& Wolfe, J. H.. 2013. Takayasu Arteritis : Criteria for Surgical Intervention Should Not Be Ignored. International Journal of Vascular Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-485622
Modern Language Association (MLA)
Perera, A. H.…[et al.]. Takayasu Arteritis : Criteria for Surgical Intervention Should Not Be Ignored. International Journal of Vascular Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-485622
American Medical Association (AMA)
Perera, A. H.& Mason, J. C.& Wolfe, J. H.. Takayasu Arteritis : Criteria for Surgical Intervention Should Not Be Ignored. International Journal of Vascular Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-485622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485622