Differentiated Thyroid Cancer : Management of Patients with Radioiodine Nonresponsive Disease
Joint Authors
Cabanillas, Maria E.
Busaidy, Naifa Lamki
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Differentiated thyroid carcinoma (papillary and follicular) has a favorable prognosis with an 85% 10-year survival.
The patients that recur often require surgery and further radioactive iodine to render them disease-free.
Five percent of thyroid cancer patients, however, will eventually succumb to their disease.
Metastatic thyroid cancer is treated with radioactive iodine if the metastases are radioiodine avid.
Cytotoxic chemotherapies for advanced or metastatic noniodine avid thyroid cancers show no prolonged responses and in general have fallen out of favor.
Novel targeted therapies have recently been discovered that have given rise to clinical trials for thyroid cancer.
Newer aberrations in molecular pathways and oncogenic mutations in thyroid cancer together with the role of angiogenesis in tumor growth have been central to these discoveries.
This paper will focus on the management and treatment of metastatic differentiated thyroid cancers that do not take up radioactive iodine.
American Psychological Association (APA)
Busaidy, Naifa Lamki& Cabanillas, Maria E.. 2012. Differentiated Thyroid Cancer : Management of Patients with Radioiodine Nonresponsive Disease. Journal of Thyroid Research،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-485634
Modern Language Association (MLA)
Busaidy, Naifa Lamki& Cabanillas, Maria E.. Differentiated Thyroid Cancer : Management of Patients with Radioiodine Nonresponsive Disease. Journal of Thyroid Research No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-485634
American Medical Association (AMA)
Busaidy, Naifa Lamki& Cabanillas, Maria E.. Differentiated Thyroid Cancer : Management of Patients with Radioiodine Nonresponsive Disease. Journal of Thyroid Research. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-485634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485634