Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab
Joint Authors
Snanoudj, Renaud
Michot, Jean-Marie
Estève, Emmanuel
Taoufik, Yacine
Pindi Sala, Taylor
Marie, Bernadette
Lambotte, Olivier
Dollat, Marion
Delfraissy, Jean-François
Lazure, Thierry
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Henoch-Schönlein purpura (HSP) is a systemic vasculitis involving small vessels with deposition of immunoglobulin A (IgA) complexes, usually affecting children.
Compared with children, HSP in adults is more severe and frequently associated with cancer.
We report the case of a 49-year-old woman with medical history of kidney transplantation for segmental glomerular hyalinosis.
Eight years after the transplantation, while taking combined immunosuppressive therapy with tacrolimus and azathioprine indicated for the prevention against transplant rejection, she developed a Henoch-Schönlein purpura.
Vasculitis involves skin and sciatic peroneal nerve and she received systemic corticosteroid treatment.
Because of four relapses and corticosteroid dependence, the patient was treated with rituximab (two intravenous infusions of 1000 mg given two weeks apart).
Successful outcome was observed along two years of follow-up.
This new case of successful use of rituximab in HSP promotes more investigations of this treatment in clinical trials.
American Psychological Association (APA)
Pindi Sala, Taylor& Michot, Jean-Marie& Snanoudj, Renaud& Dollat, Marion& Estève, Emmanuel& Marie, Bernadette…[et al.]. 2014. Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab. Case Reports in Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-485660
Modern Language Association (MLA)
Pindi Sala, Taylor…[et al.]. Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab. Case Reports in Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-485660
American Medical Association (AMA)
Pindi Sala, Taylor& Michot, Jean-Marie& Snanoudj, Renaud& Dollat, Marion& Estève, Emmanuel& Marie, Bernadette…[et al.]. Successful Outcome of a Corticodependent Henoch-Schönlein Purpura Adult with Rituximab. Case Reports in Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-485660
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485660