Recurrent Thrombotic Thrombocytopenic Purpura-Like Syndrome as a Paraneoplastic Phenomenon in Malignant Peritoneal Mesothelioma : A Case Report and Review of the Literature
Joint Authors
Bustinza-Linares, Ernesto
Socola, Francisco
Rosenblatt, Joseph D.
Loaiza-Bonilla, Arturo
Correa, Ricardo
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We report the case of an African American male with no significant past medical history presenting with recurrent, rapidly relapsing episodes of thrombotic thrombocytopenic purpura (TTP) despite aggressive treatment with several lines of treatment.
Incidentally, these episodes were associated with severe abdominal pain which eventually developed into acute abdomen and prompted exploratory laparotomy, revealing diffuse carcinomatosis with a tumor located on the left pelvis that was encasing the distal sigmoid colon.
Pathology made a final diagnosis of peritoneal mesothelioma.
TTP-like syndrome (TTP-LS) has been described as a paraneoplastic phenomenon in several malignancies but never before in the setting of malignant mesothelioma.
Paraneoplastic TTP-like syndrome has historically been associated with a dismal prognosis and particular clinical and laboratory abnormalities described in this paper.
It is of utmost importance to make a prompt determination whether TTP is idiopathic or secondary to an underlying condition because of significant differences in their prognosis, treatment, and response.
This paper also reviews the current literature regarding this challenging condition.
American Psychological Association (APA)
Socola, Francisco& Loaiza-Bonilla, Arturo& Bustinza-Linares, Ernesto& Correa, Ricardo& Rosenblatt, Joseph D.. 2012. Recurrent Thrombotic Thrombocytopenic Purpura-Like Syndrome as a Paraneoplastic Phenomenon in Malignant Peritoneal Mesothelioma : A Case Report and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-485670
Modern Language Association (MLA)
Socola, Francisco…[et al.]. Recurrent Thrombotic Thrombocytopenic Purpura-Like Syndrome as a Paraneoplastic Phenomenon in Malignant Peritoneal Mesothelioma : A Case Report and Review of the Literature. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-485670
American Medical Association (AMA)
Socola, Francisco& Loaiza-Bonilla, Arturo& Bustinza-Linares, Ernesto& Correa, Ricardo& Rosenblatt, Joseph D.. Recurrent Thrombotic Thrombocytopenic Purpura-Like Syndrome as a Paraneoplastic Phenomenon in Malignant Peritoneal Mesothelioma : A Case Report and Review of the Literature. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-485670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485670