Antioxidant Activity of Aspergillus fumigatus

Abstract EN

The antioxidant activity of Aspergillus fumigatus was assayed by different procedures and correlated with its extracellular total phenolic contents.

Different physio-chemical parameters were optimized to enhance the activity.

The culture grown under stationary conditions for 10 days at 25°C at pH 7 gave the best antioxidant activity.

Statistical approaches demonstrated sucrose and NaNO3 to be the most suitable carbon and nitrogen sources, respectively.

Response surface analysis showed 5% sucrose, 0.05% NaNO3, and incubation temperature of 35°C to be the optimal conditions for best expression of antioxidant activity.

Under these conditions, the antioxidant potential assayed through different procedures was 89.8%, 70.1%, and 70.2% scavenging effect for DPPH radical, ferrous ion and nitric oxide ion, respectively.

The reducing power showed an absorbance of 1.0 and FRAP assay revealed the activity of 60.5%.

Extracellular total phenolic content and antioxidant activity as assayed by different procedures positively correlated.