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Deficiency of 25-Hydroxyvitamin D and Dyslipidemia in Indian Subjects
Joint Authors
Mridula, K. Rukmini
Balaraju, Banda
Lingaiah, A.
Anamika, Alluri
Misra, Pradeep Kumar
Chaudhuri, Jaydip Ray
Boddu, Demudu Babu
Bandaru, Vcs Srinivasarao
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Vitamin D deficiency is widespread throughout the world.
Several reports have incriminated vitamin D deficiency as the cause of rickets, osteomalacia, and other chronic diseases.
Recent studies have suggested a possible link between deficiency of 25-hydroxyvitamin D and dyslipidemia.
Aim.
To investigate the association between 25-hydroxyvitamin D deficiency and dyslipidemia in Indian subjects.
Methodology.
We recruited 150 asymptomatic consecutive subjects from patients’ attendees at the Departments of Neurology and Medicine in Yashoda Hospital, Hyderabad, India.
Study period was from October 2011 to March 2012.
All subjects underwent 25-hydroxyvitamin D assay by chemiluminescent microparticle immunoassay, fasting blood sugar and lipid profile, calcium, phosphorus, alkaline phosphatase, and C-reactive protein (CRP).
Results.
Out of 150 subjects, men were 82 (54.6%), and mean age was 49.4 (±15.6) years.
Among risk factors, hypertension was noted in 63/150 (42%), 25-hydroxyvitamin D deficiency in 59/150 (39.3%), diabetes in 45/150 (30%), dyslipidemia in 60 (40%), smoking in 35/150 (23.3%), and alcoholism in 27/150 (18%).
Deficiency of 25-hydroxyvitamin D was significantly associated with dyslipidemia (P=0.0001), mean serum glucose (P=0.0002) mean CRP (P=0.04), and mean alkaline phosphatase (P=0.01).
Multivariate analysis showed that 25-hydroxyvitamin D deficiency was independently associated with dyslipidemia (odds ratio: 1.9; 95% CI : 1.1–3.5).
Conclusions.
We found that deficiency of 25-hydroxyvitamin D was independently associated with dyslipidemia in Indian subjects.
American Psychological Association (APA)
Chaudhuri, Jaydip Ray& Mridula, K. Rukmini& Anamika, Alluri& Boddu, Demudu Babu& Misra, Pradeep Kumar& Lingaiah, A.…[et al.]. 2013. Deficiency of 25-Hydroxyvitamin D and Dyslipidemia in Indian Subjects. Journal of Lipids،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-485953
Modern Language Association (MLA)
Chaudhuri, Jaydip Ray…[et al.]. Deficiency of 25-Hydroxyvitamin D and Dyslipidemia in Indian Subjects. Journal of Lipids No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-485953
American Medical Association (AMA)
Chaudhuri, Jaydip Ray& Mridula, K. Rukmini& Anamika, Alluri& Boddu, Demudu Babu& Misra, Pradeep Kumar& Lingaiah, A.…[et al.]. Deficiency of 25-Hydroxyvitamin D and Dyslipidemia in Indian Subjects. Journal of Lipids. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-485953
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485953