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A Pilot Study of Ketamine versus MidazolamFentanyl Sedation in Children Undergoing GI Endoscopy
Joint Authors
Lightdale, Jenifer R.
Fredette, Meghan E.
Fox, Victor L.
Mitchell, Paul D.
Zgleszewski, Steven E.
Scharff, Lisa
Mahoney, Lisa B.
Source
International Journal of Pediatrics
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Ketamine sedation has been found superior by physician report to traditional sedation regimens for pediatric endoscopy.
Goal.
To objectively compare sedation with ketamine versus midazolam/fentanyl for children undergoing gastrointestinal endoscopy.
Study.
Patients received one of two regimens and were independently monitored using a standardized rating scale.
Results.
There were 2 episodes of laryngospasm during ketamine sedation.
Univariate analyses showed patients sedated with ketamine (n=17) moved more (median 25% of procedure time versus 8%, P=.03) and required similar low levels of restraint (0.83% versus 0.25%, P=.4) as patients sedated with midazolam/fentanyl (n=20).
Age-adjusted analyses suggested that patients sedated with ketamine were comparably more quiet (P=.002).
Conclusions.
A pilot trial of ketamine at our institution was associated with episodes of laryngospasm.
In addition, children sedated with ketamine moved and required restraint similarly to patients sedated with midazolam/fentanyl.
Physician perceptions may be affected by the fact that children who received ketamine were less likely to vocalize distress.
American Psychological Association (APA)
Lightdale, Jenifer R.& Mitchell, Paul D.& Fredette, Meghan E.& Mahoney, Lisa B.& Zgleszewski, Steven E.& Scharff, Lisa…[et al.]. 2011. A Pilot Study of Ketamine versus MidazolamFentanyl Sedation in Children Undergoing GI Endoscopy. International Journal of Pediatrics،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-485973
Modern Language Association (MLA)
Lightdale, Jenifer R.…[et al.]. A Pilot Study of Ketamine versus MidazolamFentanyl Sedation in Children Undergoing GI Endoscopy. International Journal of Pediatrics No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-485973
American Medical Association (AMA)
Lightdale, Jenifer R.& Mitchell, Paul D.& Fredette, Meghan E.& Mahoney, Lisa B.& Zgleszewski, Steven E.& Scharff, Lisa…[et al.]. A Pilot Study of Ketamine versus MidazolamFentanyl Sedation in Children Undergoing GI Endoscopy. International Journal of Pediatrics. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-485973
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-485973