Von Hippel-Lindau Syndrome : Diagnosis and Management of Hemangioblastoma and Pheochromocytoma
Joint Authors
Geldners, I.
Zarina, L.
Vaganovs, P.
Plonis, J.
Vjaters, E.
Miklaševics, E.
Gardovskis, J.
Bokums, K.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Von Hippel-Lindau (VHL) syndrome is a pathological condition that causes various clinical symptoms and is difficult to diagnose.
The most common pathological lesions are hemangioblastomas of the central nervous system, retinal angiomas, renal clear cell carcinomas, and pheochromocytomas.
Case Report.
A 23-year-old female had a syncope episode in 2008.
Magnetic resonance imaging (MRI) revealed a right temporal hemangioblastoma, which was treated surgically.
Genetic screening identified a VHL gene mutation, and computed tomography (CT) revealed a left adrenal mass.
Since it was unclear whether the mass was a pheochromocytoma, or another benign or malignant tumors, laparoscopic adrenalectomy was performed.
A month after surgery, the patient complained of general fatigue, poor concentration, loss of appetite, and insomnia.
After careful clinical investigation, the patient was referred to a psychiatrist due to suspected depression, which was confirmed.
Conclusions.
VHL genetic screening should be performed in cases of hemangioblastoma.
In VHL syndrome cases, pheochromocytoma cannot always be diagnosed by biochemical catecholamine analyses; therefore, CT or MRI scanning of the abdomen must be performed.
Due to the long treatment period, some patients may develop episodes of depression, which can simulate VHL syndrome.
American Psychological Association (APA)
Vaganovs, P.& Bokums, K.& Miklaševics, E.& Plonis, J.& Zarina, L.& Geldners, I.…[et al.]. 2013. Von Hippel-Lindau Syndrome : Diagnosis and Management of Hemangioblastoma and Pheochromocytoma. Case Reports in Urology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-486010
Modern Language Association (MLA)
Vaganovs, P.…[et al.]. Von Hippel-Lindau Syndrome : Diagnosis and Management of Hemangioblastoma and Pheochromocytoma. Case Reports in Urology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-486010
American Medical Association (AMA)
Vaganovs, P.& Bokums, K.& Miklaševics, E.& Plonis, J.& Zarina, L.& Geldners, I.…[et al.]. Von Hippel-Lindau Syndrome : Diagnosis and Management of Hemangioblastoma and Pheochromocytoma. Case Reports in Urology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-486010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486010