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Mycophenolate Mofetil-Related Enterocolitis and Weight Loss : A Pediatric Case Series
Joint Authors
Saeed, Shehzad
Moore, Sean R.
Nogueira, Janaina
Katz, Avi
Maclin, Jeanine S.
Wills, Marcia L.
Hunley, Tracey E.
Rosen, Michael J.
Morris, Brian
Dykes, Dana M. H.
Polk, D. Brent
Pugh, Judith
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Mycophenolate mofetil (MMF) is an immunosuppressive medication utilized in the management of both autoimmune and solid organ transplant patients.
Diarrhea is a common gastrointestinal side effect of MMF, but more severe forms of GI symptoms are described in renal transplant patients with a distinct pattern of histopathologic change, similar to graft-versus-host disease or Crohn’s disease.
This rare entity, commonly referred to as “MMF-related enterocolitis,” has been described in adult patients, mostly in renal transplant patients, and in only two pediatric renal transplant patients.
In previously reported cases, symptoms and abnormal histopathology improve with dose reduction of MMF.
We describe a series of three pediatric patients with varied underlying disease process who presented with severe diarrhea and histopathologic findings characteristic of MMF-related enterocolitis, who share a novel finding of weight loss as a complication of MMF-related enterocolitis in pediatric patients.
American Psychological Association (APA)
Dykes, Dana M. H.& Moore, Sean R.& Polk, D. Brent& Rosen, Michael J.& Wills, Marcia L.& Morris, Brian…[et al.]. 2012. Mycophenolate Mofetil-Related Enterocolitis and Weight Loss : A Pediatric Case Series. Case Reports in Pediatrics،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-486019
Modern Language Association (MLA)
Dykes, Dana M. H.…[et al.]. Mycophenolate Mofetil-Related Enterocolitis and Weight Loss : A Pediatric Case Series. Case Reports in Pediatrics No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-486019
American Medical Association (AMA)
Dykes, Dana M. H.& Moore, Sean R.& Polk, D. Brent& Rosen, Michael J.& Wills, Marcia L.& Morris, Brian…[et al.]. Mycophenolate Mofetil-Related Enterocolitis and Weight Loss : A Pediatric Case Series. Case Reports in Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-486019
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486019