Low-Density Lipoproteins Oxidation and Endometriosis

Joint Authors

Derewianka-Polak, Magdalena
Kotarski, Jan
Kwaśniewski, Wojciech
Polak, Grzegorz
Bednarek, Wiesława
Barczyński, Bartłomiej
Wertel, Iwona

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-06-19

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

The etiopathogenesis of endometriosis still remains unknown.

Recent data provide new valuable information concerning the role of oxidative stress in the pathophysiology of the disease.

It has been proved that levels of different lipid peroxidation end products are increased in both peritoneal fluid (PF) and serum of endometriotic patients.

We assessed the concentration of oxidized low-density lipoproteins (oxLDL) in PF of 110 women with different stages of endometriosis and 119 women with serous (n=78) or dermoid (n=41) ovarian cysts, as the reference groups.

PF oxLDL levels were evaluated by ELISA.

We found that concentrations of oxLDL in PF of endometriotic women were significantly higher compared to women with serous but not dermoid ovarian cysts.

Interestingly, by analyzing concentrations of oxLDL in women with different stages of the disease, it was noted that they are significantly higher only in the subgroup of patients with stage IV endometriosis as compared to women with ovarian serous cysts.

In case of minimal, mild, and moderate disease, PF oxLDL levels were similar to those noted in reference groups.

Our results indicate that disrupted oxidative status in the peritoneal cavity of women with endometriosis may play a role in the pathogenesis of advanced stages of the disease.

American Psychological Association (APA)

Polak, Grzegorz& Barczyński, Bartłomiej& Kwaśniewski, Wojciech& Bednarek, Wiesława& Wertel, Iwona& Derewianka-Polak, Magdalena…[et al.]. 2013. Low-Density Lipoproteins Oxidation and Endometriosis. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-486048

Modern Language Association (MLA)

Polak, Grzegorz…[et al.]. Low-Density Lipoproteins Oxidation and Endometriosis. Mediators of Inflammation No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-486048

American Medical Association (AMA)

Polak, Grzegorz& Barczyński, Bartłomiej& Kwaśniewski, Wojciech& Bednarek, Wiesława& Wertel, Iwona& Derewianka-Polak, Magdalena…[et al.]. Low-Density Lipoproteins Oxidation and Endometriosis. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-486048

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-486048