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Histone Chaperones Spt6 and FACT : Similarities and Differences in Modes of Action at Transcribed Genes
Author
Source
Genetics Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-26
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The process of gene transcription requires the participation of a large number of factors that collectively promote the accurate and efficient expression of an organism's genetic information.
In eukaryotic cells, a subset of these factors can control the chromatin environments across the regulatory and transcribed units of genes to modulate the transcription process and to ensure that the underlying genetic information is utilized properly.
This article focuses on two such factors—the highly conserved histone chaperones Spt6 and FACT—that play critical roles in managing chromatin during the gene transcription process.
These factors have related but distinct functions during transcription and several recent studies have provided exciting new insights into their mechanisms of action at transcribed genes.
A discussion of their respective roles in regulating gene transcription, including their shared and unique contributions to this process, is presented.
American Psychological Association (APA)
Duina, Andrea A.. 2011. Histone Chaperones Spt6 and FACT : Similarities and Differences in Modes of Action at Transcribed Genes. Genetics Research International،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-486113
Modern Language Association (MLA)
Duina, Andrea A.. Histone Chaperones Spt6 and FACT : Similarities and Differences in Modes of Action at Transcribed Genes. Genetics Research International No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-486113
American Medical Association (AMA)
Duina, Andrea A.. Histone Chaperones Spt6 and FACT : Similarities and Differences in Modes of Action at Transcribed Genes. Genetics Research International. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-486113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486113