Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy

Joint Authors

Wang, Christina
Swerdloff, Ronald
Surampudi, Prasanth N.

Source

International Journal of Endocrinology

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-20, 20 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-03-14

Country of Publication

Egypt

No. of Pages

20

Main Subjects

Biology

Abstract EN

Hypogonadism in older men is a syndrome characterized by low serum testosterone levels and clinical symptoms often seen in hypogonadal men of younger age.

These symptoms include decreased libido, erectile dysfunction, decreased vitality, decreased muscle mass, increased adiposity, depressed mood, osteopenia, and osteoporosis.

Hypogonadism is a common disorder in aging men with a significant percentage of men over 60 years of age having serum testosterone levels below the lower limits of young male adults.

There are a variety of testosterone formulations available for treatment of hypogonadism.

Data from many small studies indicate that testosterone therapy offers several potential benefits to older hypogonadal men.

A large multicenter NIH supported double blind, placebo controlled study is ongoing, and this study should greatly enhance the information available on efficacy and side effects of treatment.

While safety data is available across many age groups, there are still unresolved concerns associated with testosterone therapy.

We have reviewed the diagnostic methods as well as benefits and risks of testosterone replacement therapy for hypogonadism in aging men.

American Psychological Association (APA)

Surampudi, Prasanth N.& Wang, Christina& Swerdloff, Ronald. 2012. Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-20.
https://search.emarefa.net/detail/BIM-486135

Modern Language Association (MLA)

Surampudi, Prasanth N.…[et al.]. Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy. International Journal of Endocrinology No. 2012 (2012), pp.1-20.
https://search.emarefa.net/detail/BIM-486135

American Medical Association (AMA)

Surampudi, Prasanth N.& Wang, Christina& Swerdloff, Ronald. Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-20.
https://search.emarefa.net/detail/BIM-486135

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-486135