Erythrocyte and Reticulocyte Indices on the LH 750 as Potential Markers of Functional Iron Deficiency
Joint Authors
Escanero, Jesús F.
Borque, Luís
Urrechaga, Eloísa
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Reticulocyte hemoglobin content (CHr) and percentage of hypochromic cells (%Hypo) are restricted to the Siemens analysers.
The aims of the study were to investigate the correlation of Red cells size factor (RSf) and low Hemoglobin density (LHD%), reported by Beckman-Coulter analysers, with CHr and %Hypo in the assessment of iron status in the presence of inflammation.
381 samples were run on both LH 750 (Beckman-Coulter) and Advia 2120 (Siemens) analysers.
Correlation between parameters were calculated and the diagnostic performance of the new parameters was assessed.
Results.
Correlation between RSf and CHr, r=0.85.
ROC curve analysis for RSf in the diagnosis of iron restricted erythropoiesis defined as CHr<28 pg: AUC 0.983; Cutoff 91.1%; Sensitivity 98.8%; Specificity 89.6% Correlation between LHD% and %Hypo, r=0.869.
ROC curve analysis for LHD% in the diagnosis of iron deficiency defined by %Hypo >5%: AUC 0.954; Cut off 6.0%; Sensitivity 96.6%; Specificity 83.2% Conclusions.
RSf and LHD% could be reliable parameters for the study of iron metabolism status.
American Psychological Association (APA)
Urrechaga, Eloísa& Borque, Luís& Escanero, Jesús F.. 2010. Erythrocyte and Reticulocyte Indices on the LH 750 as Potential Markers of Functional Iron Deficiency. Anemia،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-486177
Modern Language Association (MLA)
Urrechaga, Eloísa…[et al.]. Erythrocyte and Reticulocyte Indices on the LH 750 as Potential Markers of Functional Iron Deficiency. Anemia No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-486177
American Medical Association (AMA)
Urrechaga, Eloísa& Borque, Luís& Escanero, Jesús F.. Erythrocyte and Reticulocyte Indices on the LH 750 as Potential Markers of Functional Iron Deficiency. Anemia. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-486177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486177