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What Is New in the Understanding of Non Healing Wounds Epidemiology, Pathophysiology, and Therapies
Joint Authors
Kirketerp-Møller, K.
Høiby, N.
Trøstrup, H.
Moser, C.
Bjarnsholt, T.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Chronic wounds are a growing socioeconomic problem in the western world.
Knowledge on recalcitrant wounds relies on in vitro studies or clinical observations, and there is emerging evidence on the clinical impact of bacterial biofilm on skin healing.
Chronic wounds are locked in the inflammatory state of wound healing, and there are multiple explanations for this arrest with the theory of exaggerated proteolysis as the most commonly accepted.
Previously, there has not been enough focus on the different etiologies of chronic wounds compared to acute, healing wounds.
There is an urgent need to group chronic wounds by its cause when searching for possible diagnostic or therapeutic targets.
Good wound management should therefore consist of recognition of basic wound etiology, irrigation, and debridement in order to reduce microbial and necrotic load, frequently changed dressings, and appropriate antimicrobial and antibiofilm strategies based on precise diagnosis.
Representative sampling is required for diagnosis and antimicrobial treatment of wounds.
The present review aims at describing the impact of biofilm infections on wounds in relation to diagnosing, treatment strategies, including experimentally adjuvant approaches and animal models.
American Psychological Association (APA)
Trøstrup, H.& Bjarnsholt, T.& Kirketerp-Møller, K.& Høiby, N.& Moser, C.. 2013. What Is New in the Understanding of Non Healing Wounds Epidemiology, Pathophysiology, and Therapies. Ulcers،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-486178
Modern Language Association (MLA)
Moser, C.…[et al.]. What Is New in the Understanding of Non Healing Wounds Epidemiology, Pathophysiology, and Therapies. Ulcers No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-486178
American Medical Association (AMA)
Trøstrup, H.& Bjarnsholt, T.& Kirketerp-Møller, K.& Høiby, N.& Moser, C.. What Is New in the Understanding of Non Healing Wounds Epidemiology, Pathophysiology, and Therapies. Ulcers. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-486178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486178