Exploring Risk Factors for Follicular Lymphoma
Joint Authors
Shenoy, Pareen J.
Maggioncalda, Alison
Malik, Neha
Flowers, Christopher R.
Nastoupil, Loretta J.
Ambinder, Alexander J.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-18
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Follicular lymphoma (FL) is an indolent malignancy of germinal center B cells with varied incidence across racial groups and geographic regions.
Improvements in the classification of non-Hodgkin lymphoma subtypes provide an opportunity to explore associations between environmental exposures and FL incidence.
Our paper found that aspects of Western lifestyle including sedentary lifestyle, obesity, and diets high in meat and milk are associated with an increased risk of FL.
Diets rich in fruits and vegetables, polyunsaturated fatty acids, vitamin D, and certain antioxidants are inversely associated with FL risk.
A medical history of Sjogren's syndrome, influenza vaccination, and heart disease may be associated with FL incidence.
Associations between FL and exposure to pesticides, industrial solvents, hair dyes, and alcohol/tobacco were inconsistent.
Genetic risk factors include variants at the 6p21.32 region of the MHC II locus, polymorphisms of the DNA repair gene XRCC3, and UV exposure in individuals with certain polymorphisms of the vitamin D receptor.
Increasing our understanding of risk factors for FL must involve integrating epidemiological studies of genetics and exposures to allow for the examination of risk factors and interactions between genes and environment.
American Psychological Association (APA)
Ambinder, Alexander J.& Shenoy, Pareen J.& Malik, Neha& Maggioncalda, Alison& Nastoupil, Loretta J.& Flowers, Christopher R.. 2012. Exploring Risk Factors for Follicular Lymphoma. Advances in Hematology،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-486187
Modern Language Association (MLA)
Ambinder, Alexander J.…[et al.]. Exploring Risk Factors for Follicular Lymphoma. Advances in Hematology No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-486187
American Medical Association (AMA)
Ambinder, Alexander J.& Shenoy, Pareen J.& Malik, Neha& Maggioncalda, Alison& Nastoupil, Loretta J.& Flowers, Christopher R.. Exploring Risk Factors for Follicular Lymphoma. Advances in Hematology. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-486187
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486187