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Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy : A Meta-Analysis of Randomized Controlled Trials
Joint Authors
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
The aim of our study was to evaluate and compare the results of pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) after pancreaticoduodenectomy (PD).
Methods.
Published data of randomized clinical trials (RCTs) comparing the clinically relevant outcomes of PG versus PJ after PD were analyzed.
Two reviewers assessed the quality of each trial and collected data independently.
The Cochrane Collaboration’s RevMan 5.0 software was used for statistical analysis.
Proportions were combined, and the odds ratio (OR) with its 95% CI was used as the effect size estimate.
Results.
Four RCTs published in 1995 or later were included in this meta-analysis, in which 276 patients underwent PG and 277 patients underwent PJ followed PD.
In the combined results of PG versus PJ, a significant difference in the morbidity of intra-abdominal complications (OR, 0.34; 95% CI, 0.23–0.49; P<0.00001) was found, but no significant difference could be found for pancreatic fistula (OR, 0.69; 95% CI, 0.42–1.12 , P=0.13) mortality (OR, 1.09; 95% CI, 0.42–2.83; P=0.87), recovery with no complications (OR, 1.26; 95% CI, 0.90–1.78; P=0.18), biliary fistula (OR, 0.55; 95% CI, 0.22–1.35; P=0.19), or in delayed gastric emptying (OR, 0.55; 95% CI, 0.33–1.01; P=0.06).
Conclusions.
Current RCTs suggest that PG is better than PJ for pancreatic reconstruction after PD.
American Psychological Association (APA)
Shen, YinFeng& Jin, WenYin. 2012. Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy : A Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486254
Modern Language Association (MLA)
Shen, YinFeng& Jin, WenYin. Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy : A Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-486254
American Medical Association (AMA)
Shen, YinFeng& Jin, WenYin. Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy : A Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486254
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486254