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Transfusion Strategy : Impact of Haemodynamics and the Challenge of Haemodilution
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-06
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Blood transfusion is associated with increased morbidity and mortality and numerous reports have emphasised the need for reduction.
Following this there is increased attention to the concept of patient blood management.
However, bleeding is relatively common following cardiac surgery and is further enhanced by the continued antiplatelet therapy policy.
Another important issue is that cardiopulmonary bypass leads to haemodilution and a potential blood loss.
The basic role of blood is oxygen transport to the organs.
The determining factors of oxygen delivery are cardiac output, haemoglobin, and saturation.
If oxygen delivery/consumption is out of balance, the compensation mechanisms are simple, as a decrease in one factor results in an increase in one or two other factors.
Patients with coexisting cardiac diseases may be of particular risk, but studies indicate that patients with coexisting cardiac diseases tolerate moderate anaemia and may even benefit from a restrictive transfusion regimen.
Further it has been shown that patients with reduced left ventricular function are able to compensate with increased cardiac output in response to bleeding and haemodilution if normovolaemia is maintained.
In conclusion the evidence supports that each institution establishes its own patient blood management strategy to both conserve blood products and maximise outcome.
American Psychological Association (APA)
Jakobsen, Carl-Johan. 2014. Transfusion Strategy : Impact of Haemodynamics and the Challenge of Haemodilution. Journal of Blood Transfusion،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-486261
Modern Language Association (MLA)
Jakobsen, Carl-Johan. Transfusion Strategy : Impact of Haemodynamics and the Challenge of Haemodilution. Journal of Blood Transfusion No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-486261
American Medical Association (AMA)
Jakobsen, Carl-Johan. Transfusion Strategy : Impact of Haemodynamics and the Challenge of Haemodilution. Journal of Blood Transfusion. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-486261
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486261