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Microglia : An Active Player in the Regulation of Synaptic Activity
Joint Authors
Ji, Kyungmin
Tsirka, Stella E.
Miyauchi, Jeremy
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Synaptic plasticity is critical for elaboration and adaptation in the developing and developed brain.
It is well established that astrocytes play an important role in the maintenance of what has been dubbed “the tripartite synapse”.
Increasing evidence shows that a fourth cell type, microglia, is critical to this maintenance as well.
Microglia are the resident macrophages of the central nervous system (CNS).
Because of their well-characterized inflammatory functions, research has primarily focused on their innate immune properties.
The role of microglia in the maintenance of synapses in development and in homeostasis is not as well defined.
A number of significant findings have shed light on the critical role of microglia at the synapse.
It is becoming increasingly clear that microglia play a seminal role in proper synaptic development and elimination.
American Psychological Association (APA)
Ji, Kyungmin& Miyauchi, Jeremy& Tsirka, Stella E.. 2013. Microglia : An Active Player in the Regulation of Synaptic Activity. Neural Plasticity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-486276
Modern Language Association (MLA)
Ji, Kyungmin…[et al.]. Microglia : An Active Player in the Regulation of Synaptic Activity. Neural Plasticity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-486276
American Medical Association (AMA)
Ji, Kyungmin& Miyauchi, Jeremy& Tsirka, Stella E.. Microglia : An Active Player in the Regulation of Synaptic Activity. Neural Plasticity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-486276
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486276