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The Employment of Leukotriene Antagonists in Cutaneous Diseases Belonging to Allergological Field
Joint Authors
Nettis, Eustachio
Elisabetta, Di Leo
Calogiuri, Gianfranco
Montinaro, Vincenzo
Vacca, Angelo
D'Erasmo, Maddalena
Ferrannini, Antonio
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Leukotrienes (LTs) are potent biological proinflammatory mediators.
LTC4, LTD4, and LTE4 are more frequently involved in chronic inflammatory responses and exert their actions binding to a cysteinyl-LT 1 (CysLT1) receptor and a cysteinyl-LT 2 (CysLT2) receptor.
LTs receptor antagonists available for clinical use demonstrate high-affinity binding to the CysLT1 receptor.
In this paper the employment of anti-LTs in allergic cutaneous diseases is analyzed showing that several studies have recently reported a beneficial effects of these agents (montelukast and zafirlukast as well as zileuton) for the treatment of some allergic cutaneous related diseases-like chronic urticaria and atopic eczema although their proper application remains to be established.
American Psychological Association (APA)
Nettis, Eustachio& D'Erasmo, Maddalena& Elisabetta, Di Leo& Calogiuri, Gianfranco& Montinaro, Vincenzo& Ferrannini, Antonio…[et al.]. 2010. The Employment of Leukotriene Antagonists in Cutaneous Diseases Belonging to Allergological Field. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-486354
Modern Language Association (MLA)
Nettis, Eustachio…[et al.]. The Employment of Leukotriene Antagonists in Cutaneous Diseases Belonging to Allergological Field. Mediators of Inflammation No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-486354
American Medical Association (AMA)
Nettis, Eustachio& D'Erasmo, Maddalena& Elisabetta, Di Leo& Calogiuri, Gianfranco& Montinaro, Vincenzo& Ferrannini, Antonio…[et al.]. The Employment of Leukotriene Antagonists in Cutaneous Diseases Belonging to Allergological Field. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-486354
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486354