Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease

Abstract EN

Objectives.

Ninety-one fetuses with dilated or hypertrophic cardiomyopathy (DCM, HCM) and myocarditis were studied.

Results.

Group 1 “DCM” included 19 fetuses: 13 with hydrops (FH) and 5 with associated extracardiac anomalies (ECAs) (15.8%).

Group 2 “Myocarditis” included twelve fetuses, having 11 with FH.

Group 3 “HCM” included sixty fetuses: 26 had associated ECAs, 17 had maternal diabetes, and 17 were “idiopathic”; however, in one case, a metabolic disorder was found postnatally, and 4 had familiarity for HCM.

Outcomes.

Ten cases opted for termination of pregnancy.

Two cases with DCM and 1 with HCM were lost at follow-up.

Out of the cases that continued pregnancy, with known follow-up, mortality was 68.75% in Group 1, 63.6% in Group 2, and 31.3% in Group 3 (the majority with severe ECAs).

Surviving cases with DCM and myocarditis improved, 2 with HCM worsened, 6 remained stable, and 26 improved or normalized.

Conclusions.

Our data show more severe prognosis in DCM and myocarditis and forms with severe associated ECAs.