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Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer
Joint Authors
Clarke, Stephen J.
McLachlan, Andrew J.
He, Xiaoye
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Populations around the world are aging, and the associated increase in cancer incidence has led to the recognition of the importance of geriatric oncology.
Chronological age is a poor determinant of pharmacological response to cancer chemotherapy agents.
Age-associated changes in physiology and organ function have a significant impact on the clinical pharmacology of cancer chemotherapy agents used in cancer treatment.
Altered response to medicines in older people is a consequence of changes in body composition, organ function, concomitant pathophysiology, multiple medications, genetic determinants of drug response, and patient's clinical status.
These issues highlight the need to individualize the management of cancer in the older people with consideration of age-related changes in the clinical pharmacology of cancer drugs, analgesics, and adjunctive therapies.
American Psychological Association (APA)
He, Xiaoye& Clarke, Stephen J.& McLachlan, Andrew J.. 2011. Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer. Current Gerontology and Geriatrics Research،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-486414
Modern Language Association (MLA)
He, Xiaoye…[et al.]. Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer. Current Gerontology and Geriatrics Research No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-486414
American Medical Association (AMA)
He, Xiaoye& Clarke, Stephen J.& McLachlan, Andrew J.. Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer. Current Gerontology and Geriatrics Research. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-486414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486414