BOLD-Perfusion Coupling during Monocular and Binocular Stimulation
Joint Authors
Gauthier, Claudine
Hoge, Richard D.
Source
International Journal of Biomedical Imaging
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-03-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Previous studies have suggested that during selective activation of a subset of the zones comprising a columnar system in visual cortex, perfusion increases uniformly in all columns of the system, while increases in oxidative metabolism occur predominantly in the activated columns.
This could lead to disproportionately large blood oxygenation level-dependent (BOLD) signal increases for a given flow increase during monocular (relative to binocular) stimulation, due to contributions from columns which undergo large increases in perfusion with little or no change in oxidative metabolism.
In the present study, we sought to test this hypothesis by measuring BOLD-perfusion coupling ratios in spatially averaged signals over V1 during monocular and binocular visual stimulation.
It was found that, although withholding input to one eye resulted in statistically significant decreases in BOLD and perfusion signals in primary visual cortex, the ratio between BOLD and perfusion increases did not change significantly.
These results do not support a gross mismatch between spatial patterns of flow and metabolism response during monocular stimulation.
American Psychological Association (APA)
Gauthier, Claudine& Hoge, Richard D.. 2008. BOLD-Perfusion Coupling during Monocular and Binocular Stimulation. International Journal of Biomedical Imaging،Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-486420
Modern Language Association (MLA)
Gauthier, Claudine& Hoge, Richard D.. BOLD-Perfusion Coupling during Monocular and Binocular Stimulation. International Journal of Biomedical Imaging No. 2008 (2008), pp.1-6.
https://search.emarefa.net/detail/BIM-486420
American Medical Association (AMA)
Gauthier, Claudine& Hoge, Richard D.. BOLD-Perfusion Coupling during Monocular and Binocular Stimulation. International Journal of Biomedical Imaging. 2008. Vol. 2008, no. 2008, pp.1-6.
https://search.emarefa.net/detail/BIM-486420
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486420