Virgin Coconut Oil Prevents Blood Pressure Elevation and Improves Endothelial Functions in Rats Fed with Repeatedly Heated Palm Oil

Joint Authors

Qodriyah, Hj Mohd Saad
Kamisah, Yusof
Nurul-Iman, Badlishah Sham
Jaarin, Kamsiah

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-06-05

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

This study was performed to explore the effects of virgin coconut oil (VCO) in male rats that were fed with repeatedly heated palm oil on blood pressure, plasma nitric oxide level, and vascular reactivity.

Thirty-two male Sprague-Dawley rats were divided into four groups: (i) control (basal diet), (ii) VCO (1.42 mL/kg, oral), (iii) five-times-heated palm oil (15%) (5HPO), and (iv) five-times-heated palm oil (15%) and VCO (1.42 mL/kg, oral) (5HPO + VCO).

Blood pressure was significantly increased in the group that was given the 5HPO diet compared to the control group.

Blood pressure in the 5HPO + VCO group was significantly lower than the 5HPO group.

Plasma nitric oxide (NO) level in the 5HPO group was significantly lower compared to the control group, whereas in the 5HPO + VCO group, the plasma NO level was significantly higher compared to the 5HPO group.

Aortic rings from the 5HPO group exhibited attenuated relaxation in response to acetylcholine and sodium nitroprusside as well as increased vasoconstriction to phenylephrine compared to the control group.

Aortic rings from the 5HPO + VCO group showed only attenuated vasoconstriction to phenylephrine compared to the 5HPO group.

In conclusion, VCO prevents blood pressure elevation and improves endothelial functions in rats fed with repeatedly heated palm oil.

American Psychological Association (APA)

Nurul-Iman, Badlishah Sham& Kamisah, Yusof& Jaarin, Kamsiah& Qodriyah, Hj Mohd Saad. 2013. Virgin Coconut Oil Prevents Blood Pressure Elevation and Improves Endothelial Functions in Rats Fed with Repeatedly Heated Palm Oil. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-486471

Modern Language Association (MLA)

Nurul-Iman, Badlishah Sham…[et al.]. Virgin Coconut Oil Prevents Blood Pressure Elevation and Improves Endothelial Functions in Rats Fed with Repeatedly Heated Palm Oil. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-486471

American Medical Association (AMA)

Nurul-Iman, Badlishah Sham& Kamisah, Yusof& Jaarin, Kamsiah& Qodriyah, Hj Mohd Saad. Virgin Coconut Oil Prevents Blood Pressure Elevation and Improves Endothelial Functions in Rats Fed with Repeatedly Heated Palm Oil. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-486471

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-486471