Molecular Pathogenesis of Cholangiocarcinoma
Joint Authors
Source
International Journal of Hepatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Epidemiological data from the last years show an increasing trend of incidence and mortality of cholangiocarcinoma (CC) worldwide.
Many pathophysiologic aspects of this neoplasia are still unknown and need to be fully discovered.
However, several progresses were recently made in order to establish the molecular mechanisms involved in the transformation and growth of malignant cholangiocytes.
The principal concept that at least seems to be established is that cholangiocarcinogenesis is a multistep cellular process evolving from a normal condition of the epithelial biliary cells through a chronic inflammation status ending with malignant transformation.
The bad prognosis related to CC justifies why a better identification of the molecular mechanisms involved in the growth and progression of this cancer is required for the development of effective preventive measures and valid treatment regimens.
This Paper describes the scientific progresses made in the last years in defining the molecular pathways implicated in the generation of this devastating disease.
American Psychological Association (APA)
Fava, G.& Lorenzini, I.. 2011. Molecular Pathogenesis of Cholangiocarcinoma. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486565
Modern Language Association (MLA)
Fava, G.& Lorenzini, I.. Molecular Pathogenesis of Cholangiocarcinoma. International Journal of Hepatology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-486565
American Medical Association (AMA)
Fava, G.& Lorenzini, I.. Molecular Pathogenesis of Cholangiocarcinoma. International Journal of Hepatology. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486565