Patterns of Change in Cognitive Function over Six Months in Adults with Chronic Heart Failure
Joint Authors
Moelter, Stephen T.
Glaser, Dale
Riegel, Barbara
Lee, Christopher S.
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Few investigators have studied cognition over time in adults with heart failure (HF).
A battery of neuropsychological tests was administered to 279 adults with chronic systolic or diastolic HF at baseline, three and six months.
Growth mixture modeling (GMM) was used to model the measure anticipated to be most sensitive, the digit symbol substitution task (DSST).
We describe how and why the DSST patterns change over time.
Other measures of cognition were examined to identify consistency with the DSST patterns.
The sample was predominantly male (63.2%), Caucasian (62.7%), mean age 62 years.
The best fit GMM revealed two trajectories of DSST scores: Average processing speed group (40.5%) and Below Average processing speed (59.9%).
Neither group changed significantly over the six month study.
Other measures of cognition were consistent with the DSST patterns.
Factors significantly associated with increased odds of being in the Below Average processing speed group included older age, male gender, Non-Caucasian race, less education, higher ejection fraction, high comorbid burden, excessive daytime sleepiness, and higher BMI.
As some of the factors related to cognitive impairment are modifiable, research is needed to identify interventions to preserve and improve cognition in these patients.
American Psychological Association (APA)
Riegel, Barbara& Lee, Christopher S.& Glaser, Dale& Moelter, Stephen T.. 2012. Patterns of Change in Cognitive Function over Six Months in Adults with Chronic Heart Failure. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-486625
Modern Language Association (MLA)
Riegel, Barbara…[et al.]. Patterns of Change in Cognitive Function over Six Months in Adults with Chronic Heart Failure. Cardiology Research and Practice No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-486625
American Medical Association (AMA)
Riegel, Barbara& Lee, Christopher S.& Glaser, Dale& Moelter, Stephen T.. Patterns of Change in Cognitive Function over Six Months in Adults with Chronic Heart Failure. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-486625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486625